Knippel, James Levi; Ye, Yuxuan; Buchwald, Stephen L. published the artcile< Enantioselective C2-Allylation of Benzimidazoles Using 1,3-Diene Pronucleophiles>, Product Details of C16H22N2O3, the main research area is benzimidazole aryl alkadiene copper catalyst enantioselective regioselective allylation; aryl alkenylbenzimidazole preparation.
Previously, several enantioselective allylation reactions of benzimidazoles were reported that functionalize the nucleophilic nitrogen atom. To the reversal of this inherent selectivity, N-allylation by using electrophilic N-OPiv benzimidazoles with readily available 1,3-dienes as nucleophile precursors were described. CuH-catalyzed approach utilized mild reaction conditions, exhibited broad functional-group compatibility and exclusively formed the C2-allylated product with excellent stereoselectivity.
Organic Letters published new progress about 1,3-Alkadienes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 197638-83-8 belongs to class piperazines, and the molecular formula is C16H22N2O3, Product Details of C16H22N2O3.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics