Basu, Debjit; Richters, Andre; Rauh, Daniel published their research in Bioorganic & Medicinal Chemistry on August 1 ,2015. The article was titled 《Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR [Erratum to document cited in CA163:000258]》.Recommanded Product: 4-(3-Aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine The article contains the following contents:
On page 2768, Figure 1B contained an error in structure CO-1686; the corrected figure is given. After reading the article, we found that the author used 4-(3-Aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine(cas: 1213269-26-1Recommanded Product: 4-(3-Aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine)
4-(3-Aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine(cas: 1213269-26-1) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Recommanded Product: 4-(3-Aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics