The author of 《Novel practical deprotection of N-Boc compounds using fluorinated alcohols》 were Choy, Jason; Jaime-Figueroa, Saul; Jiang, Laurence; Wagner, Paul. And the article was published in Synthetic Communications in 2008. Recommanded Product: 4-(Piperazin-1-yl)-1H-indole The author mentioned the following in the article:
The thermolytic deprotection of N-Boc compounds was accomplished using F3CCH2OH or (F3C)2CHOH as solvents. Even though the cleavage of the tert-butylcarbamate (Boc) group can be achieved at solvent reflux temperature, the deprotection process was significantly accelerated under microwave-assisted conditions. The practicality of this methodol. was demonstrated on alkyl, aryl, and heteroaromatic N-Boc-amines. In the experiment, the researchers used many compounds, for example, 4-(Piperazin-1-yl)-1H-indole(cas: 84807-09-0Recommanded Product: 4-(Piperazin-1-yl)-1H-indole)
4-(Piperazin-1-yl)-1H-indole(cas: 84807-09-0) belongs to piperazines. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid).Recommanded Product: 4-(Piperazin-1-yl)-1H-indole
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics