Quality Control of 4-Methyl-1-piperazinesulfonyl ChlorideOn November 1, 2019 ,《Photoredox-Catalyzed Generation of Sulfamyl Radicals: Sulfonamidation of Enol Silyl Ether with Chlorosulfonamide》 appeared in Journal of Organic Chemistry. The author of the article were Luo, Qiyu; Mao, Runyu; Zhu, Yan; Wang, Yonghui. The article conveys some information:
A novel and practical photoredox-catalyzed generation of sulfamyl radicals followed by radical sulfonamidation of enol silyl ether has been described. Diverse functionalized β-ketosulfonamides ArCOCH2SO2NRR1 (Ar = 4-MeC6H4, 4-BrC6H4, 2-FC6H4, etc.; R = H, Me, Et, etc.; R1 = H, Me, Et, etc.) were prepared in modest to excellent yields under mild and economic reaction conditions through the present catalytic protocol. Furthermore, the methodol. developed provides an efficient and convenient approach to the synthesis of the antiseizure drug Zonisamide. In the experiment, the researchers used 4-Methyl-1-piperazinesulfonyl Chloride(cas: 1688-95-5Quality Control of 4-Methyl-1-piperazinesulfonyl Chloride)
4-Methyl-1-piperazinesulfonyl Chloride(cas: 1688-95-5) is a member of sulfamide. Sulfamide was used in the synthesis of: Schiff bases of the type ArCH=NSO2NH2; 1H,3H-2,1,3-benzothiadiazin-4-one-2,2-dioxide (BTDD); sulfamide analogs of oleoylethanolamide analogs in a study of PPARα activation.Quality Control of 4-Methyl-1-piperazinesulfonyl Chloride
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics