Zhou, Min; Ni, Chuanfa; Zeng, Yuwen; Hu, Jinbo published the artcile< Trifluoromethyl Benzoate: A Versatile Trifluoromethoxylation Reagent>, Application In Synthesis of 229009-40-9, the main research area is trifluoromethyl benzoate versatile trifluoromethoxylation reagent; trifluoromethoxylation halogenation aryne.
Trifluoromethyl benzoate (TFBz) is developed as a new shelf-stable trifluoromethoxylation reagent, which can be easily prepared from inexpensive starting materials using KF as the only fluorine source. The synthetic potency of TFBz is demonstrated by trifluoromethoxylation-halogenation of arynes, nucleophilic substitution of alkyl (pseudo)halides, cross-coupling with aryl stannanes, and asym. difunctionalization of alkenes. The unprecedented trifluoromethoxylation-halogenation of arynes proceeds smoothly at room temperature with the aid of a crown ether-complexed potassium cation, which significantly stabilizes the trifluoromethoxide anion derived from TFBz.
Journal of the American Chemical Society published new progress about Alkynes, arynes Role: RCT (Reactant), RACT (Reactant or Reagent). 229009-40-9 belongs to class piperazines, and the molecular formula is C11H17BN2O2, Application In Synthesis of 229009-40-9.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics