On March 28, 2013, Kolbe, Ludger; Scherner, Cathrin published a patent.Related Products of 53788-12-8 The title of the patent was Heterocyclocarbonyl aminothiazoles, cosmetic or dermatological preparations containing said heterocyclocarbonyl aminothiazoles, and use thereof to combat or prevent undesired pigmentation of the skin. And the patent contained the following:
The invention relates to cosmetic and dermatol. preparations having an effective content of one or more heterocyclocarbonyl aminothiazoles of formula I and to the use thereof for the cosmetic or dermatol. treatment and/or prophylaxis of undesired skin pigmentation. Compounds of formula I wherein R1 is morpholino, piperidin-1-yl, piperazin-1-yl, etc.; R2 is H, (un)branched C1-24 alkyl, (un)branched C1-24 alkenyl, etc.; X is H, Ph, 2,4-dihydroxyphenyl, etc.; Y is H, aryl, COO-aryl, etc.; as free bases and their cosmetic and dermatol. acceptable salts, are claimed. Example compound II was prepared by thioamidation of 4-morpholinecarbonyl chloride with thiourea followed by cyclocondensation of the resulting N-morpholinocarbonylthiourea with 2-bromo-2′,4′-bismethoxycarbonyloxyacetophenone. All the invention compounds were evaluated for their ability to inhibit pigmentation. From the assay, it was determined that example compound II exhibited 97% of inhibition. The experimental process involved the reaction of 4-Ethyl-piperazine-1-carbonyl chloride(cas: 53788-12-8).Related Products of 53788-12-8
The Article related to heterocyclocarbonyl aminothiazole preparation cosmetic dermatol treatment pigmentation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Related Products of 53788-12-8
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics