On May 15, 2020, Kim, Jeong Hyeon; Han, Hyo Won; Han, Hyeong Jun published a patent.Category: piperazines The title of the patent was Infectious disease-treating drug screening method based on pluripotent stem cell-derived macrophages. And the patent contained the following:
The infectious disease-treating or preventing drug screening method uses pluripotent stem cell-derived macrophages (eMAC) with more similar gene expression with macrophages (hMDM) in human blood as compared with existing mouse-derived cell line (Raw264.7) and human-derived macrophage cell line (ThP-1) used for screening tuberculostatic drug. The screening method has an excellent screening effect when compared with the conventional screening methods. A tuberculostatic drug screening method that can be useful for new drug development and quality control of existing tuberculostatic drugs is provided. The experimental process involved the reaction of 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate(cas: 86393-32-0).Category: piperazines
The Article related to infectious disease drug screening pluripotent stem cell macrophage, Placeholder for records without volume info and other aspects.Category: piperazines
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics