On October 1, 1996, Turel, Iztok; Bukovec, Peter published an article.Recommanded Product: 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate The title of the article was Comparison of the thermal stability of ciprofloxacin and its compounds. And the article contained the following:
The thermal behavior of ciprofloxacin, its hydrochloride and 2 copper (II) compounds of ciprofloxacin was studied by thermogravimetry, DSC, evolved gas anal. and IR spectroscopy. In all the compounds studied, profound differences in the carboxylic (C:O) absorption were found after heating, which can be explained by the rearrangement of the hydrogen bonds. The experimental process involved the reaction of 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate(cas: 86393-32-0).Recommanded Product: 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate
The Article related to ciprofloxacin copper complex thermal stability, Pharmaceuticals: Pharmaceutics and other aspects.Recommanded Product: 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics