Hupertz, Vera published the artcileSusceptibility of Campylobacter pylori isolated from pediatric and adult patients to seven new quinolone antibiotics and nalidixic acid, Safety of Temafloxacin hydrochloride, the main research area is Campylobacter sensitivity quinolone bactericide nalidixate.
The susceptibility of 26 strains of C. pylori to 7 new quinolone antibiotics and nalidixic acid was determined All strains were resistant to nalidixic acid. Difloxacin, A-56620, A-62254, and ciprofloxacin were equally effective against the test strains with MICs ranging from 0.06 to 2.0 μg/mL. Fleroxacin, amifloxacin, perfloxacin, and norfloxacin showed only moderate activity against C. pylori. The new quinolone agents, which are bactericidal, may prove useful in the eradication of C. pylori from the gastric mucosa.
Chemotherapy (Basel, Switzerland) published new progress about Helicobacter pylori. 105784-61-0 belongs to class piperazines, name is Temafloxacin hydrochloride, and the molecular formula is C21H19ClF3N3O3, Safety of Temafloxacin hydrochloride.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics