Huang, Yiyun’s team published research in Bioorganic & Medicinal Chemistry Letters in 15 | CAS: 180698-19-5

Bioorganic & Medicinal Chemistry Letters published new progress about 180698-19-5. 180698-19-5 belongs to piperazines, auxiliary class Piperazine,Benzene, name is 1-Biphenyl-4-yl-piperazine, and the molecular formula is C16H18N2, Synthetic Route of 180698-19-5.

Huang, Yiyun published the artcileSynthesis of potent and selective serotonin 5-HT1B receptor ligands, Synthetic Route of 180698-19-5, the publication is Bioorganic & Medicinal Chemistry Letters (2005), 15(21), 4786-4789, database is CAplus and MEDLINE.

A series of serotonin 5-HT1B ligands were synthesized and evaluated for their potency and selectivity against other 5-HT receptor subtypes. Many of these new compounds displayed high affinity and selectivity for the 5-HT1B receptor and one compound was found to have the in vitro binding profile necessary for development as a PET radioligand.

Bioorganic & Medicinal Chemistry Letters published new progress about 180698-19-5. 180698-19-5 belongs to piperazines, auxiliary class Piperazine,Benzene, name is 1-Biphenyl-4-yl-piperazine, and the molecular formula is C16H18N2, Synthetic Route of 180698-19-5.

Referemce:
https://en.wikipedia.org/wiki/Piperazine,
Piperazines – an overview | ScienceDirect Topics