Nadigar, Mohan R. published the artcileSynthesis and in vitro antibacterial activity of some novel sulfonamide derivatives bearing 1,4-disubstituted-1,2,4-oxadiazole moiety, SDS of cas: 113534-02-4, the publication is Journal of Applicable Chemistry (Lumami, India) (2013), 2(4), 722-729, database is CAplus.
A strategic synthesis of 1-[(2,5-dimethoxyphenyl)sulfonyl]-4-{5-[substituted]-1,2,4-oxadiazol-3-yl}piperazine, involves construction of 1,2,4-oxadiazole ring by intermol. condensation of tert-butyl-4-(N-hydroxycarbamimidoyl)piperazine-1-carboxylate with 3-(trifluromethoxy)benzoic acid. Structures of the newly synthesized compounds were established by IR, 1H NMR, 13C NMR, LC-MS and CHNS spectroscopic evidences. All the newly synthesized compounds were tested for their in vitro antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus cereus. Tested compounds showed good antibacterial activities when compared to the reference ciprofloxacin. Five compounds showed good activity against tested organisms.
Journal of Applicable Chemistry (Lumami, India) published new progress about 113534-02-4. 113534-02-4 belongs to piperazines, auxiliary class Piperazine,Nitrile,Amide, name is tert-Butyl 4-cyanopiperazine-1-carboxylate, and the molecular formula is C10H17N3O2, SDS of cas: 113534-02-4.
Referemce:
https://en.wikipedia.org/wiki/Piperazine,
Piperazines – an overview | ScienceDirect Topics