Zheng, Chun-zhi’s team published research in Huaxue Shiji in 32 | CAS: 67914-60-7

Huaxue Shiji published new progress about 67914-60-7. 67914-60-7 belongs to piperazines, auxiliary class Piperazine,Benzene,Phenol,Amide, name is 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, and the molecular formula is C3H3Br2ClO, Safety of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone.

Zheng, Chun-zhi published the artcileNew process for synthesis of 1-acetyl-4-(4-hydroxyphenyl)piperazine, Safety of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, the publication is Huaxue Shiji (2010), 32(10), 952-954, database is CAplus.

The synthesis of the target compound was achieved (37.5% overall yield) by a sequence involving a chlorination, cyclization and acylation using bis(2-chloroethyl)amine hydrochloride and aminophenol as reactants. The product thus obtained [i.e., 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone] was confirmed by IR, 1H-NMR.

Huaxue Shiji published new progress about 67914-60-7. 67914-60-7 belongs to piperazines, auxiliary class Piperazine,Benzene,Phenol,Amide, name is 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone, and the molecular formula is C3H3Br2ClO, Safety of 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone.

Referemce:
https://en.wikipedia.org/wiki/Piperazine,
Piperazines – an overview | ScienceDirect Topics