Immobilized palladium nanoparticles on silica functionalized N-propylpiperazine sodium N-propionate (SBPPSP): catalytic activity evaluation in copper-free Sonogashira reaction was written by Niknam, Khodabakhsh;Deris, Abdollah;Panahi, Farhad;Reza Hormozi Nezhad, M.. And the article was included in Journal of the Iranian Chemical Society in 2013.Electric Literature of C7H16N2 This article mentions the following:
An efficient heterogeneous palladium catalyst system has been developed based on immobilization of Pd nanoparticles on silica-bonded N-propylpiperazine sodium N-propionate (SBPPSP) substrate. SBPPSP substrate can stabilize the Pd nanoparticles effectively so that it can improve their stability against aggregation. In addition, grafted piperazine species on to the silica backbone prevent the removing of Pd nanoparticles from the substrate surface. Transmission electron microscopy (TEM) of catalyst is shown the size of Pd nanoparticles, also it confirmed by particle size analyzer which shown the average size of 21 nm for Pd. The catalytic activity of these catalysts was investigated in the Sonogashira reaction. The catalyst could be recycled several times without appreciable loss in catalytic activity. In the experiment, the researchers used many compounds, for example, 1-Propylpiperazine (cas: 21867-64-1Electric Literature of C7H16N2).
1-Propylpiperazine (cas: 21867-64-1) belongs to piperazine derivatives. The piperazine scaffold is often found in biologically active compounds in different therapeutic areas. These therapeutic areas include antifungals, antidepressants, antivirals, and serotonin receptor (5-HT) antagonists/agonists. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Electric Literature of C7H16N2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics