Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series. [Erratum to document cited in CA153:382905] was written by Coteron, Jose M.;Catterick, David;Castro, Julia;Chaparro, Maria J.;Diaz, Beatriz;Fernandez, Esther;Ferrer, Santiago;Gamo, Francisco J.;Gordo, Mariola;Gut, Jiri;de las Heras, Laura;Legac, Jennifer;Marco, Maria;Miguel, Juan;Munoz, Vicente;Porras, Esther;de la Rosa, Juan C.;Ruiz, Jose R.;Sandoval, Elena;Ventosa, Pilar;Rosenthal, Philip J.;Fiandor, Jose M.. And the article was included in Journal of Medicinal Chemistry in 2010.Synthetic Route of C7H16N2 This article mentions the following:
On page 6143, Table 12 is incorrect; the corrections to the table are given. On page S7, in Table S6, the structure for compound 144 is incorrect. On pages S29, S34, S36, S38-39, Table S9 is incorrect; the corrections to the Table are given. In the experiment, the researchers used many compounds, for example, 1-Propylpiperazine (cas: 21867-64-1Synthetic Route of C7H16N2).
1-Propylpiperazine (cas: 21867-64-1) belongs to piperazine derivatives. Piperazine is a fairly basic compound and is an amine solvent. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid).Synthetic Route of C7H16N2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics