Molecular iodine-catalyzed facile procedure for N-Boc protection of amines was written by Varala, Ravi;Nuvula, Sreelatha;Adapa, Srinivas R.. And the article was included in Journal of Organic Chemistry in 2006.Application of 780705-64-8 This article mentions the following:
An efficient and practical protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of a catalytic amount of mol. iodine under solvent-free conditions at ambient temperature is presented. In the experiment, the researchers used many compounds, for example, tert-Butyl 4-(pyrimidin-2-yl)piperazine-1-carboxylate (cas: 780705-64-8Application of 780705-64-8).
tert-Butyl 4-(pyrimidin-2-yl)piperazine-1-carboxylate (cas: 780705-64-8) belongs to piperazine derivatives. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Application of 780705-64-8
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics