Comparative evaluation of efficacies of dl-tetramisole and piperazine against Ascaridia galli in chickens was written by Altaif, K. I.. And the article was included in American Journal of Veterinary Research in 1972.Formula: C4H12Cl2N2 This article mentions the following:
Dl-tetramisole (I) [5036-02-2] (20 and 40 mg/kg) administered in drinking water proved 87.7 and 99.0% efficacious, resp., against mature Ascaridia galli in chickens, whereas 20 mg/kg I mixed with feed gave a 63.0% reduction of the fecal egg count. Piperazine-2HCl [142-64-3] (260 mg/kg) given in drinking water resulted in a 96.4% reduction in fecal egg count whereas when given in the feed a 79.0% reduction was observed In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3Formula: C4H12Cl2N2).
Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. The piperazine scaffold is often found in biologically active compounds in different therapeutic areas. These therapeutic areas include antifungals, antidepressants, antivirals, and serotonin receptor (5-HT) antagonists/agonists. Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.Formula: C4H12Cl2N2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics