112257-24-6, 1-Boc-3-Carbamoylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
The compound (S) -5- (1 – ((tert-butoxycarbonyl) amino) ethyl) -2- (3- (cyclopropylmethoxy) -4-(difluoromethoxy) phenyl ) -oxazole-4-carboxylic Acid (300mg, 0.64mmol), the compound 3-carbamoylpiperazine-1-carboxylate (153mg, 0.64mmol), 1- ethyl-3- (3-dimethylaminopropyl Aminopropyl)carbodiimide hydrochloride (250mg, 1.3mmol) and N- hydroxy-7-aza-benzotriazole (174mg, 1.3mmol) wasdissolved in methylene Methane (25mL), and the conditions under 0 C, to this solution was added dropwiseN, N- diisopropylethylamine (0.33mL, 1.93mmol), stirred at room temperature 5 H, add water (10mL ¡Á 3),dried over anhydrous Na 2 SO 4 organic phase was dried, the solvent was removed concentrate was subjected tocolumn chromatography (eluent: Petroleumether / EtOAc (v / v) = 2/3), to give 220mg white solid, yield: 50%., 112257-24-6
As the paragraph descriping shows that 112257-24-6 is playing an increasingly important role.
Reference£º
Patent; Guangdong East Sunshine Pharmaceutical Co., Ltd; Zhang, Ying jun; Liu, Bing; Yu, Tian Zhu; Zhang, Xiang Yu; (348 pag.)CN105399698; (2016); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics