128102-16-9, (R)-4-Benzyl 1-Boc-2-methylpiperazine-4-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 1 15Btert-Butyl 2-methylpiperazine- 1 -carboxylate[00728] A solution of 4-benzyl 1-tert-butyl 2-methylpiperazine- 1,4-dicarboxylate (4.8 g, 14.4 mmol) in methanol (25 mL) was added 480 mg of 10% Pd/C and stirred at room temperature under hydrogen overnight. Filtered and concentrated to give the title product (2.8 g, yield 97%) as colorless oil. ^-NMR (400 MHz, CDC13) delta (ppm): 1.21 (d, J= 6.8 Hz, 3H), 1.46 (s, 9H), 2.64-2.70 (m, 1H), 2.74- 2.78 (m, 1H), 2.88-3.01 (m, 3H), 3.78 (d, J= 12.4 Hz, 1H), 4.16 (m, 1H); LC-MS (ESI) m/z: 201 (M+l)+., 128102-16-9
Big data shows that 128102-16-9 is playing an increasingly important role.
Reference£º
Patent; BIOMARIN PHARMACEUTICAL INC.; WANG, Bing; CHU, Daniel; WO2011/130661; (2011); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics