Brief introduction of Cyclohexyl(piperazin-1-yl)methanone

27561-62-2, 27561-62-2 Cyclohexyl(piperazin-1-yl)methanone 3437502, apiperazines compound, is more and more widely used in various fields.

27561-62-2, Cyclohexyl(piperazin-1-yl)methanone is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The mixture of compound 3 (1g, 4.6mmol) and 95% ethanol (30ml) was added to morpholine (0.4g, 4.6mmol).The mixture was stirred at room temperature for 30min, then warmed up to 60C. After the starting 3 was completely consumed (the reaction courses was monitored by TLC), evaporation of the ethanol, the crude yellow compound 4j was obtained and purified by preparative thin-layer chromatography over silica gel PF 254 (2mm, ethyl acetate: petroleum ether=1:1). Yield: 78%.

27561-62-2, 27561-62-2 Cyclohexyl(piperazin-1-yl)methanone 3437502, apiperazines compound, is more and more widely used in various fields.

Reference:
Article; Xu, Feng; Yang, Zhen-Zhen; Jiang, Jun-Rong; Pan, Wan-Gui; Yang, Xiao-Le; Wu, Jian-Yong; Zhu, Yan; Wang, John; Shou, Qi-Yang; Wu, Han-Gui; Bioorganic and Medicinal Chemistry Letters; vol. 26; 13; (2016); p. 3042 – 3047;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics