Analyzing the synthesis route of 5747-48-8

The synthetic route of 5747-48-8 has been constantly updated, and we look forward to future research findings.

5747-48-8, 11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

5747-48-8, (E)-2-(4-(dibenzo[b,fJ[l,4]thiazepin-l l-yl)piperazin-l-yl)ethanol-d4 prepared according to general method A in 52 % yield. This material was carried forward in crude form.[126] 1H NMR (CDCl3) delta 2.52 – 2.57 (m, 2H), 2.63 – 2.68 (m, 2H), 3.47 – 3.60 (m, 2H), 3.65 (t, 2H, J= 6.4), 6.89 (t, IH, J= 7.6), 7.07 (d, IH, J= 7.6), 7.15 – 7.19 (m, IH), 7.27 – 7.36 (m, 3H), 7.39 (d, IH, J= 7.6) 7.5 l (d, IH, J= 7.3). LCMS mlz 343.9 [M + H].

The synthetic route of 5747-48-8 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; CONCERT PHARMACEUTICALS INC.; WO2008/66620; (2008); A2;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics