Some tips on (S)-tert-Butyl 2-ethylpiperazine-1-carboxylate

Big data shows that 325145-35-5 is playing an increasingly important role.

325145-35-5, (S)-tert-Butyl 2-ethylpiperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

At 60 ° C (S) chloro-1- (chloromethyl) -2-methyl-3-nitrobenzene (D23, 1.232 g) in DMF (20 mL) was added (S)-2-ethylpiperazine-1-carboxylic acid tert-butyl ester(1 g) and K2CO3 (1.935 g). After taking a over night, The mixture is poured into ice / water,Then extracted with DCM (3 x 100 mL).The combined organic layers were dehydrated by Na2S04,Filter & apos; with concentrated to produce a yellow oil,Purification by column chromatography (using EpsilonAlpha: PE = 5percent) gave the title compound ( 3 g) as a yellow solid, 325145-35-5

Big data shows that 325145-35-5 is playing an increasingly important role.

Reference:
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; LEI, HUI; MA, XIN; REN, FENG; LIN, XICHEN; MARQUIS, ROBERT W., JR; (139 pag.)TW2017/14884; (2017); A;,
Piperazine – Wikipedia
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