The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(Bromomethyl)-4-iodobenzene(SMILESS: IC1=CC=C(CBr)C=C1,cas:16004-15-2) is researched.Category: quinoxaline. The article 《One pot synthesis of isocyano-containing, densely functionalised gem-difluoroalkenes from α-trifluoromethyl alkenes, alkyl halides and TosMIC》 in relation to this compound, is published in Organic Chemistry Frontiers. Let’s take a look at the latest research on this compound (cas:16004-15-2).
A base-promoted one-pot, three-component reaction of TosMIC with α-trifluoromethyl alkenes and alkyl halides for the synthesis of isocyano- containing, densely functionalized gem-difluoroalkenes were reported. This protocol displayed broad scope and excellent functional group compatibility. The products were used as precursors to various medicinally relevant fluorine- or heterocycle-containing compouds.
Here is a brief introduction to this compound(16004-15-2)COA of Formula: C7H6BrI, if you want to know about other compounds related to this compound(16004-15-2), you can read my other articles.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics