Derivation of elementary reaction about 53562-86-0

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Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Proceedings of the National Academy of Sciences of the United States of America called Remarkably diastereoselective synthesis of a chiral biphenyl diphosphine ligand and its application in asymmetric hydrogenation, Author is Qiu, Liqin; Wu, Jing; Chan, Shusun; Au-Yeung, Terry T.-L.; Ji, Jian-Xin; Guo, Rongwei; Pai, Cheng-Chao; Zhou, Zhongyuan; Li, Xingshu; Fan, Qing-Hua; Chan, Albert S. C., which mentions a compound: 53562-86-0, SMILESS is C[C@H](O)CC(OC)=O, Molecular C5H10O3, Application of 53562-86-0.

Essentially complete atropdiastereoselectivity was realized in the preparation of biaryl diphosphine dioxide by asym. intramol. Ullmann coupling and oxidative coupling with central-to-axial chirality transfer. A bridged C2-sym. biphenylphosphine ligand possessing addnl. chiral centers on the linking unit of the biphenyl groups was synthesized. No resolution step was required for the preparation of the enantiomerically pure chiral ligand. These findings offer a general and practical tool for the development of previously uninvestigated atropdiastereomeric biaryl phosphine ligands. The diphosphine ligand was highly effective in the asym. hydrogenation of α- and β-keto esters, 2-(6′-methoxy-2′-naphthyl)propenoic acid, β-(acylamino)acrylates, and enol acetates.

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Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics