Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Bromopriopionaldehydediethylacetal, is researched, Molecular C7H15BrO2, CAS is 3400-55-3, about Reactions of α-bromopropionaldehyde and its diethyl acetal with triethyl phosphite and triphenylphosphine.Safety of 2-Bromopriopionaldehydediethylacetal.
Reactions of MeCHBrCH(OEt)2 (I) with (EtO)3P (II) gave, via MeCBr:CHOEt (III), (EtO)2P(O)CMe:CHOEt, which on hydrolysis yielded (EtO)2P(O)CHMeCHO. Reaction of MeCHBrCHO (IV) with II gave MeCH:CHOP(O)(OEt)2. Heating I with Ph3P in benzene gave Ph3PO and [Ph3P+Et]Br- with III and MeCH:CHCHMeCH(OEt)2 as by-products. III reacted with Ph3P to give [Ph3P+CMe:CHOEt]Br-, hydrolysis of which yielded [Ph3P+CHMeCHO]Br-. IV reacted with Ph3P to give [MeCH:CHOP+Ph3]Br-.
From this literature《Reactions of α-bromopropionaldehyde and its diethyl acetal with triethyl phosphite and triphenylphosphine》,we know some information about this compound(3400-55-3)Safety of 2-Bromopriopionaldehydediethylacetal, but this is not all information, there are many literatures related to this compound(3400-55-3).
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics