Frelek, Jadwiga; Gorecki, Marcin; Jazwinski, Jaroslaw; Masnyk, Marek; Ruskowska, Patrycja; Szmigielski, Rafal published the article 《Configurational assignment of vic-amino alcohols from their circular dichroism spectra with dirhodium tetracetate as an auxiliary chromophore》. Keywords: configuration vic amino alc CD dirhodium tetracetate auxiliary chromophore.They researched the compound: (S)-1-(Dimethylamino)propan-2-ol( cas:53636-17-2 ).Recommanded Product: (S)-1-(Dimethylamino)propan-2-ol. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:53636-17-2) here.
The CD spectra of a variety of vic-amino alcs. in the presence of dirhodium tetraacetate as an auxiliary chromophore were measured in ethanol as the solvent. The method was tested with several model compounds, representing both acyclic and cyclic amino alcs., including biol. important adrenergic drugs as well as amino sugars. The study demonstrated that the sign of the Cotton effects is determined by the preferred helicity of the O-C-C-N unit in the chiral complex formed in situ. The combined anal. of the CD, UV-vis, 1H and 13C NMR indicated predisposition to form chiral complexes by initial coordination of the amino alc. at the axial coordination site followed by migration to the equatorial position. Finally, after migration of the ligand to an equatorial position(s) a bridging or a chelating complex is formed. Hence, vic-amino alcs. in ethanol act as bidentate ligands in the end.
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Piperazine – Wikipedia,
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