The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-Fluoroindoline, is researched, Molecular C8H8FN, CAS is 2343-22-8, about Rh(III)-Catalyzed direct C-7 amination of indolines with anthranils, the main research direction is pyrimidylindoline anthranil preparation rhodium catalyst amination; pyrimidylindolinyl aminobenzaldehyde preparation.Quality Control of 5-Fluoroindoline.
An efficient and practical method for the C-7 amination of indolines via Rh(III)-catalyzed C-H activation was reported. This reaction afforded various C-7 aminated indolines in good to excellent yields by using readily available anthranils as the aminating agents. The corresponding indolines with an amino and a carbonyl group together provided an opportunity for the construction and modification of diverse indoles and indolines in the pharmaceutical industry.
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Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics