The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1,10-Phenanthroline( cas:66-71-7 ) is researched.SDS of cas: 66-71-7.Selmi, Ahmed; Omezzine, Marwene; Mahmoudi, Riadh M.; Puschmann, Horst; Ennaceur, Nasreddine published the article 《Structural, Spectroscopic, Antiferromagnetic and in vitro antiproliferative studies of copper(II) pyrophosphate complex against Human breast cancer cell lines》 about this compound( cas:66-71-7 ) in Journal of Molecular Structure. Keywords: bipyridine phenanthroline copper pyrophosphate preparation crystal mol structure antitumor. Let’s learn more about this compound (cas:66-71-7).
In purpose to search for compounds of biol. interest, authors have succeeded in synthesizing a copper complex with polypyridine ligands. The architecture of the compound consists of O,N-donor entities, the pyrophosphate anion HP2O3-7 and the two heterocyclic mols., 1,10-phenanthroline and 2,2′-bipyridine. X-ray diffraction study proves that their compound crystallizes in a monoclinic cell of space group P21/n. The at. arrangement can be described by the aggregation of [(C10H8N2)(C12H10N2)Cu2(H2O)2(HP2O7)]+ cation, which contributes to the macrocyclic compound-complex. The second sphere of the cationic complex is localized the anion ClO-4 to complete the neutrality. Magnetic studies show an antiferromagnetic coupling exchange between metal copper ions which mediated throw neighboring oxygen atom belonging from the pyrophosphate anion. The biol. antiproliferative activity of the sample shows a relatively high cytotoxicity IC50 resp. toward MCF-7 breast cancer cell lines.
After consulting a lot of data, we found that this compound(66-71-7)SDS of cas: 66-71-7 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics