Application In Synthesis of 1-(Bromomethyl)-4-iodobenzene. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1-(Bromomethyl)-4-iodobenzene, is researched, Molecular C7H6BrI, CAS is 16004-15-2, about Iodinated Choline Transport-Targeted Tracers.
We present a novel series of radioiodinated tracers and potential theranostics for diseases accompanied by pathol. function of proteins involved in choline transport. Unlike choline analogs labeled with 11C or 18F that are currently used in the clinic, the iodinated compounds described herein are applicable in positron emission tomog., single-photon emission computed tomog., and potentially in therapy, depending on the iodine isotope selection. Moreover, favorable half-lives of iodine isotopes result in much less challenging synthesis by isotope exchange reaction. Six of the described compounds were nanomolar ligands, and the best compound possessed an affinity 100-fold greater than that of choline. Biodistribution data of 125I-labeled ligands in human prostate carcinoma bearing (PC-3) mice revealed two compounds with a biodistribution profile superior to that of [18F]fluorocholine.
Although many compounds look similar to this compound(16004-15-2)Application In Synthesis of 1-(Bromomethyl)-4-iodobenzene, numerous studies have shown that this compound(SMILES:IC1=CC=C(CBr)C=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
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Piperazines – an overview | ScienceDirect Topics