Polo, Efrain; Ferrer-Pertuz, Karoll; Trilleras, Jorge; Quiroga, Jairo; Gutierrez, Margarita published the artcile< Microwave-assisted one-pot synthesis in water of carbonylpyrazolo[3,4-b]pyridine derivatives catalyzed by InCl3 and sonochemical assisted condensation with aldehydes to obtain new chalcone derivatives containing the pyrazolopyridinic moiety>, Name: 1-Boc-4-(4-Formylphenyl)piperazine, the main research area is arylidene pyrazoloquinolinone preparation diastereoselective; pyrazolopyridinyl chalcone preparation diastereoselective; pyrazolopyridine green preparation aldehyde Claisen Schmidt base catalyst ultrasound; aminopyrazole formaldehyde beta diketone domino condensation indium catalyst microwave.
An efficient method was developed for the synthesis of pyrazolo[3,4-b]pyridine derivatives, e.g., I, via In-catalyzed one-pot three-component condensation of 3-methyl-1-phenyl-1H-pyrazolo-5-amine, formaldehyde (as paraformaldehyde) and β-diketones under microwave irradiation in aqueous media. This process had advantages of simple operation, higher yields, low cost and environmentally benign procedure. Further sonochem.-assisted Claisen-Schmidt condensation of pyrazolopyridines I with aryl aldehydes under basic catalysis afforded arylidene-pyrazolo[3,4-b]quinolinones II [RR1 = (CH2)2; Ar = Ph, 4-MeOC6H4, 1-methylimidazol-2-yl, etc.] and pyrazolo[3,4-b]pyridinyl chalcones II [R = H, R1 = Me].
RSC Advances published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 197638-83-8 belongs to class piperazines, and the molecular formula is C16H22N2O3, Name: 1-Boc-4-(4-Formylphenyl)piperazine.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics