On March 31, 2005, Rizk, N. M. H.; El-Kosasy, A. M. published an article.SDS of cas: 86393-32-0 The title of the article was Novel ciprofloxacin ion membrane sensors based on β-cyclodextrin. And the article contained the following:
Ciprofloxacin (CF) is sensitively detected in pharmaceuticals and human serum by potentiometric method. The proposed method based on the use of β-cyclodextrin (βCD) as ionophore, o-nitrophenyl octyl ether as plasticizer and potassium tetraphenyl-fluoromethylborate as a cationic additive, in polyvinyl chloride (PVC) matrix for the fabrication and construction of ciprofloxacin sensors. The conventional and microsized coated wire types are prepared, characterized compared and applied. The proposed sensors exhibit linear response in the range of 1×10-1-1×10-4 M ciprofloxacin with cationic slopes of 30.2±0.5 and 29.3±0.6 mV decade-1 at 25° over the pH range 4-6 for conventional and microsized coated wire, resp. Ciprofloxacin electrodes show reasonable selectivity towards some related compounds, amino acids, common organic and inorganic cations. The investigated procedures are successfully applied to the determination of ciprofloxacin in bulk powder, pharmaceutical products and human serum. Results with mean accuracy 99.8±0.6 % and 99.6±0.7 % for the nominal concentrations were obtained for conventional and microsized coated wire, resp., which compare well with data obtained using spectrophotometric (UV-Vis) method. The experimental process involved the reaction of 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate(cas: 86393-32-0).SDS of cas: 86393-32-0
The Article related to ciprofloxacin sensor beta cyclodextrin ionophore potassium tetraphenyl fluoromethylborate, cationic additive pharmaceutical preparation nitrophenyl octyl ether plasticizer and other aspects.SDS of cas: 86393-32-0
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