Source-specific ecological risks and critical source identification of PPCPs in surface water: Comparing urban and rural areas was written by Wu, Yanqi;Song, Shuai;Chen, Xinchuang;Shi, Yajuan;Cui, Haotian;Liu, Ying;Yang, Shengjie. And the article was included in Science of the Total Environment in 2023.Synthetic Route of C16H18FN3O3 The following contents are mentioned in the article:
To control the concentrations of pharmaceutical and personal care products (PPCPs) in the surface water of urban and rural areas, it is important to explore the spatial variation in source-specific ecol. risks and identify critical sources. Here, we focused on 22 PPCPs found in the effluent from wastewater treatment plants and surface water in Tianjin, and source-specific risk was quant. apportioned combining pos. matrix factorization with ecol. risk assessment. Results showed that rural areas exhibited a more severe contamination level than urban areas. Medical wastewater (30.1%) accounted for the highest proportion, while domestic sewage posed the greatest threat to aquatic ecosystems. The incidence of potential risks (RQ > 0.01) caused by domestic sewage in urban areas (88.9%) was higher than that in rural areas (75.9%). However, PPCP risks caused by farmland drainage, aquaculture, and livestock discharge were mainly distributed in rural areas. The critical source identified in the entire region was domestic sewage (weight, 0.36), and its weight (0.51) in urban areas was greater than that in rural areas (0.32). The impact of aquaculture (weight, 0.16) in rural areas was noteworthy. These findings may contribute to developing environmental management strategies in key areas to help alleviate PPCP contamination worldwide. This study involved multiple reactions and reactants, such as 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (cas: 70458-96-7Synthetic Route of C16H18FN3O3).
1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (cas: 70458-96-7) belongs to piperazine derivatives. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid).Synthetic Route of C16H18FN3O3
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics