Winkelmann, E. et al. published their research in Arzneimittel-Forschung in 1986 | CAS: 21867-64-1

1-Propylpiperazine (cas: 21867-64-1) belongs to piperazine derivatives. Industrial applications of piperazine include the manufacture of plastics, resins, pesticides and brake fluids. Although many piperazine derivatives occur naturally, piperazine itself can be synthesized by reacting alcoholic ammonia with 1,2-dichloroethane, by the action of sodium and ethylene glycol on ethylene diamine hydrochloride, or by reduction of pyrazine with sodium in ethanol.SDS of cas: 21867-64-1

Chemotherapeutically active anthraquinones. II. Aminomethylanthraquinones was written by Winkelmann, E.;Raether, W.. And the article was included in Arzneimittel-Forschung in 1986.SDS of cas: 21867-64-1 This article mentions the following:

Anthraquinones [I, R = OAc, S2CNEt2, Sc(:NH)NH2, NH2, dialkylamino, heterocyclic, S(CH2)2NEt2, OC6H4NH2, R1 = H, XR, R2 = H, XR, Me, R3 = R5 = H, OH, heterocyclic, R4 = H, OH] were prepared and tested in vitro and in vivo (in hamster) against Entamoeba聽histolytica and interferon-inducing property in mice. Activity against Trichomonas聽foetus (in mice) was also tested. Most of the compounds showed chemotherapeutic activities in these tests. Structure-activity relations are discussed. In the experiment, the researchers used many compounds, for example, 1-Propylpiperazine (cas: 21867-64-1SDS of cas: 21867-64-1).

1-Propylpiperazine (cas: 21867-64-1) belongs to piperazine derivatives. Industrial applications of piperazine include the manufacture of plastics, resins, pesticides and brake fluids. Although many piperazine derivatives occur naturally, piperazine itself can be synthesized by reacting alcoholic ammonia with 1,2-dichloroethane, by the action of sodium and ethylene glycol on ethylene diamine hydrochloride, or by reduction of pyrazine with sodium in ethanol.SDS of cas: 21867-64-1

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics