Category: 3400-55-3

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Effectiveness and Mechanism of the Ene(amido) Group in Activating Iron for the Catalytic Asymmetric Transfer Hydrogenation of Ketones, published in 2021-01-25, which mentions a compound: 3400-55-3, Name is 2-Bromopriopionaldehydediethylacetal, Molecular C7H15BrO2, Recommanded Product: 3400-55-3.

π-Interacting ligands of the diphosphino amido-ene(amido) type are effective in activating Fe to resemble the properties of precious metals in the catalytic asym. transfer hydrogenation of ketones. To further verify the effectiveness of the ene(amido) group, the authors synthesized four amine(imine) diphosphine Fe precatalyst complexes with substituents at α and β positions relative to imino groups (1-3) or with enlarged chelate ring sizes (5,5,6-membered rings) (4). In comparison with the parent trans-(R,R)-[Fe(CO)(Cl)(PPh2CH2CH:NCHPhCHPhNHCH2CH2PPh2)]BF4, the introduction of a Me group in 1 and 2 reduced the catalytic activity but led to undiminished enantioselectivity as reaction proceeded. In comparison to the Fe complexes 1-3 with a 5,5,5-coordination geometry, the complex 4 derived from the new (R,R)-P-NH-NH2 tridentate ligand showed high reactivity comparable to that of I but was unfortunately not enantioselective. The catalytic reactivity of 1, 2, and 4 illustrates the effectiveness of the ene(amido) group. An electronic structure study on the important catalytic intermediate amido-ene(amido) complex 1b proved that Fe was activated by an addnl. π-back-donation-interaction ligand to participate in the traditional metal-ligand bifunctional pathway in the asym. transfer hydrogenation reactions.

If you want to learn more about this compound(2-Bromopriopionaldehydediethylacetal)Recommanded Product: 3400-55-3, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(3400-55-3).

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《The preparation of α-bromoacetals》. Authors are Marvell, Elliot N.; Joncich, Micheal J..The article about the compound:2-Bromopriopionaldehydediethylacetalcas:3400-55-3,SMILESS:CC(Br)C(OCC)OCC).Recommanded Product: 2-Bromopriopionaldehydediethylacetal. Through the article, more information about this compound (cas:3400-55-3) is conveyed.

Acetals can be brominated readily by N-bromosuccinimide (I). The predominant products from the di-Et acetals of AcH (II), EtCHO (III), PrCHO (IV), and iso-PrCHO (V) were the α-bromoacetals. A by-product containing a more reactive Br was noted in each case. PhCH(OEt)2 and I yielded EtOBz. I is better than Br for the preparation of α-bromoacetals. Me(CH2)5CHO and I yielded no pure product. I added to the acetal (equimolar quantities) in direct sunlight (temperature kept below 40°), the mixture cooled, filtered, washed with CCl4, the filtrate and washings shaken 30 min. with NaHCO3, the organic layer separated and distilled yielded the α-bromoacetal, of which the yield(%), b.p./mm., n20D, d2020, and MRD calculated (found) are: II, 57, 67°/15, 1.4401, 1.286, 40.9 (40.4); III, 68, 82-5°/30, 1.4371, 1.207, 45.6 (45.9); IV, 24, 74-7°/15, 1.4418, 1.170, 50.2 (50.9); V, 59, 87.5°/30, 1.4345, 1.141, 50.2 (50.6).

If you want to learn more about this compound(2-Bromopriopionaldehydediethylacetal)Recommanded Product: 2-Bromopriopionaldehydediethylacetal, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(3400-55-3).

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics