Category: 53562-86-0

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Asymmetric bioreduction of benzyl acetoacetate to its corresponding alcohol, benzyl (S)-(+)-3-hydroxybutyrate by the yeast Candida schatavii MY 1831, published in 1996-11-25, which mentions a compound: 53562-86-0, mainly applied to benzyl acetoacetate asym reduction hydroxybutyrate Candida, Synthetic Route of C5H10O3.

The screening of 35 microbial strains yielded 13 of them as suitable biocatalysts for the asym. bioreduction of benzyl acetoacetate to its corresponding alc. benzyl (S)-(+)-3-hydroxybutyrate. The production of benzyl (S)-(+)-3-hydroxybutyrate with an elevated optical purity of 93% was achieved when employing the yeast Candida schatavii strain MY 1831.

Compounds in my other articles are similar to this one((S)-Methyl 3-hydroxybutanoate)Synthetic Route of C5H10O3, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about The role of acid in accelerating the asymmetric reduction of methyl acetoacetate with BINAP-chloro-(p-cymene)-Ru chloride complex.Category: piperazines.

The effect of addition of catalytic amounts of organic and inorganic acid on the asym. hydrogenation of Me acetoacetate with Ru-BINAP complex was studied. An increased activity was observed which was found to be dependent on the strength and the amount of acid added up to saturation It was proposed that the added acids protonate the carbonyl bond and hence facilitate the hydride transfer.

In some applications, this compound(53562-86-0)Category: piperazines is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Jo, Donghyun; Lee, Jae Sung; Lee, Kyung Hee researched the compound: (S)-Methyl 3-hydroxybutanoate( cas:53562-86-0 ).COA of Formula: C5H10O3.They published the article 《Enantio-differentiating hydrogenation of methyl acetoacetate over modified nickel catalysts: Effects of nickel dispersion on the enantio-selectivity of catalysts》 about this compound( cas:53562-86-0 ) in Research on Chemical Intermediates. Keywords: nickel silica hydrogenation catalyst enantioselectivity tartaric acid reduction temperature; methyl acetoacetate hydrogenation enantioselectivity catalyst malic acid sorption. We’ll tell you more about this compound (cas:53562-86-0).

Enantio-differentiating hydrogenation of Me acetoacetate was performed over fumed silica-supported Ni catalysts modified with solution of (R,R)-tartaric acid or (S)-malic acid and NaBr. The reduction temperature of supported Ni was the most important factor determining the enantioselectivity of catalysts. The reduction temperature affected Ni dispersion, quantity, and coverage by the agent. The enantioselectivity (ee) of (R,R)-tartaric acid and (S)-malic acid was compared at various reduction temperatures (R,R)-tartaric acid, with two hydroxyl groups, showed optimum coverage on Ni surface and maximum ee of 72% at reduction temperature of 973 K. In contrast, (S)-malic acid with one hydroxyl group showed monotonous decrease in ee and decreasing adsorbed amount with increasing reduction temperature

In some applications, this compound(53562-86-0)COA of Formula: C5H10O3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about Ligand-acceleration by a chiral modifier in the enantioselective hydrogenation of methyl acetoacetate on a Raney nickel catalyst: effect of a modifier configuration.Recommanded Product: 53562-86-0.

Reaction rate and enantioselectivity of asym. hydrogenation of Me acetoacetate were studied over Raneynickel catalysts modified with (R,R)-tartaric acid, malic acid, or succinic acid to reveal the impacts of the modifier configuration. Catalysts comodified with two different acids were also examined to confirm the conclusions. From anal. of the enantiomer ratio of the hydrogenation product and initial reaction rate, tartaric acid (TA) was found to have dual functions as the modifier during the hydrogenation; effective suppression of the racemic catalysis on bare Ni surface and extensive enantiodifferentiating ligand acceleration by adsorbed TA. It was demonstrated that each adsorbed chiral modifier mol. independently takes part in the enantiospecific hydrogenation.

As far as I know, this compound(53562-86-0)Recommanded Product: 53562-86-0 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

Ema, Tadashi; Sugiyama, Yasushi; Fukumoto, Minoru; Moriya, Hiroyuki; Cui, Jing-Nan; Sakai, Takashi; Utaka, Masanori published an article about the compound: (S)-Methyl 3-hydroxybutanoate( cas:53562-86-0,SMILESS:C[C@H](O)CC(OC)=O ).Category: piperazines. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:53562-86-0) through the article.

An NADPH-dependent reductase that shows reducing activity for 1-chloro-2-hexanone has been purified from bakers’ yeast. SDS-PAGE and gel filtration suggested that the purified reductase is a monomeric enzyme with a mol. weight of ca. 37 kDa. Asym. reduction of several carbonyl compounds using the purified reductase has been carried out. 1-Chloro-2-hexanone, 1-acetoxy-2-heptanone, Me acetoacetate, Et pyruvate, 1-chloro-2,4-pentanedione, and 2,4-hexanedione were reduced to the corresponding alcs. with high enantiomeric purities (>98% ee). The reductase showed high specificity constants (kcat/Km = 103-105 s-1 M-1) and relatively low Michaelis constants (Km = 10-4-10-3 M) for all the substrates examined

As far as I know, this compound(53562-86-0)Category: piperazines can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

Safety of (S)-Methyl 3-hydroxybutanoate. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about Highly Effective Chiral Ortho-Substituted BINAPO Ligands (o-BINAPO): Applications in Ru-Catalyzed Asymmetric Hydrogenations of β-Aryl-Substituted β-(Acylamino)acrylates and β-Keto Esters. Author is Zhou, Yong-Gui; Tang, Wenjun; Wang, Wen-Bo; Li, Wenge; Zhang, Xumu.

A novel family of chiral ortho-substituted BINAPO ligands (o-BINAPO) I (R = H, Me, Ph, 3,5-Me2C6H3; R1 = Ph, 3,5-Me2C6H3) were prepared from the corresponding binaphthols and diarylchlorophosphines; complexes of I with [(p-cymene)RuCl2]2 were highly efficient catalysts for asym. hydrogenation of β-aryl-substituted β-(acylamino)acrylates R2C(AcNH):CHCO2R3 (R2 = Ph, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-MeC6H4, 4-MeOC6H4, 2-MeC6H4, 2-MeOC6H4; R3 = Me, Et) and β-aryl-substituted β-keto esters R4COCH2CO2R5 (R4 = Ph, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-MeC6H4, 4-MeOC6H4, 2-MeC6H4, 2-MeOC6H4, Me, ClCH2; R5 = Me, Et) to give nonracemic β-amino acid esters R2CH(NHAc)CH2CO2R3 (R2 = Ph, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-MeC6H4, 4-MeOC6H4, 2-MeC6H4, 2-MeOC6H4; R3 = Me, Et) and β-hydroxy esters R4CH(OH)CH2CO2R5 (R4 = Ph, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-MeC6H4, 4-MeOC6H4, 2-MeC6H4, 2-MeOC6H4, Me, ClCH2; R5 = Me, Et). While most asym. hydrogenation catalysts are effective only with single stereoisomers of β-amidoesters, hydrogenation catalysts prepared from I and [(p-cymene)RuCl2]2 hydrogenated E/Z mixture of β-aryl-substituted β-(acylamino)acrylates enantioselectively to give β-(acetylamino)esters in high enantiomeric excesses. E.g., Me 3-phenyl-3-acetylamino-2-propenoate PhC:NHAcCHCO2Me (prepared from Me 3-phenyl-3-oxopropanoate by addition of ammonium acetate, precipitation, and acylation with acetic anhydride) undergoes enantioselective hydrogenation in ethanol at 80 psi and 50° in the presence of a ruthenium catalyst prepared from I (R = 3,5-Me2C6H3; R1 = Ph) and [(p-cymene)RuCl2]2 to give PhCH(NHAc)CH2CO2Me in 99% ee.

When you point to this article, it is believed that you are also very interested in this compound(53562-86-0)Safety of (S)-Methyl 3-hydroxybutanoate and due to space limitations, I can only present the most important information.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

SDS of cas: 53562-86-0. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about Influence of Synthesis Conditions on the Structure of Nickel Nanoparticles and their Reactivity in Selective Asymmetric Hydrogenation. Author is Arrigo, Rosa; Gallarati, Simone; Schuster, Manfred E.; Seymour, Jake M.; Gianolio, Diego; da Silva, Ivan; Callison, June; Feng, Haosheng; Proctor, John E.; Ferrer, Pilar; Venturini, Federica; Grinter, David; Held, Georg.

Unsupported and SiO2-supported Ni nanoparticles (NPs) were synthesized via hot-injection colloidal route using oleylamine (OAm) and trioctylphosphine (TOP) as reducing and protective agents, resp. By adopting a multi-length scale(coating process) structural characterization, it was found that by changing equivalent of OAm and TOP not only the size of the nanoparticles is affected but also the Ni electronic structure. The synthesized NPs were modified with (R,R)-tartaric acid (TA) and investigated in the asym. hydrogenation of Me acetoacetate to chiral methyl-3-hydroxy butyrate. The comparative anal. of structure and catalytic performance for the synthesized catalysts has enabled us to identify a Ni metallic active surface, whereby the activity increases with the size of the metallic domains. Conversely, at the high conversion obtained for the unsupported NPs there was no impact of particle size on the selectivity. (R)-selectivity was very high only on catalysts containing pos. charged Ni species such as over the SiO2-supported NiO NPs. This work shows that the chiral modification of metallic Ni NPs with TA is insufficient to maintain high selectivity towards the (R)-enantiomer at long reaction times and provides guidance for the engineering of long-term stable enantioselective catalysts.

When you point to this article, it is believed that you are also very interested in this compound(53562-86-0)SDS of cas: 53562-86-0 and due to space limitations, I can only present the most important information.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about The role of acid in accelerating the asymmetric reduction of methyl acetoacetate with BINAP-chloro-(p-cymene)-Ru chloride complex.Category: piperazines.

The effect of addition of catalytic amounts of organic and inorganic acid on the asym. hydrogenation of Me acetoacetate with Ru-BINAP complex was studied. An increased activity was observed which was found to be dependent on the strength and the amount of acid added up to saturation It was proposed that the added acids protonate the carbonyl bond and hence facilitate the hydride transfer.

In some applications, this compound(53562-86-0)Category: piperazines is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Jo, Donghyun; Lee, Jae Sung; Lee, Kyung Hee researched the compound: (S)-Methyl 3-hydroxybutanoate( cas:53562-86-0 ).COA of Formula: C5H10O3.They published the article 《Enantio-differentiating hydrogenation of methyl acetoacetate over modified nickel catalysts: Effects of nickel dispersion on the enantio-selectivity of catalysts》 about this compound( cas:53562-86-0 ) in Research on Chemical Intermediates. Keywords: nickel silica hydrogenation catalyst enantioselectivity tartaric acid reduction temperature; methyl acetoacetate hydrogenation enantioselectivity catalyst malic acid sorption. We’ll tell you more about this compound (cas:53562-86-0).

Enantio-differentiating hydrogenation of Me acetoacetate was performed over fumed silica-supported Ni catalysts modified with solution of (R,R)-tartaric acid or (S)-malic acid and NaBr. The reduction temperature of supported Ni was the most important factor determining the enantioselectivity of catalysts. The reduction temperature affected Ni dispersion, quantity, and coverage by the agent. The enantioselectivity (ee) of (R,R)-tartaric acid and (S)-malic acid was compared at various reduction temperatures (R,R)-tartaric acid, with two hydroxyl groups, showed optimum coverage on Ni surface and maximum ee of 72% at reduction temperature of 973 K. In contrast, (S)-malic acid with one hydroxyl group showed monotonous decrease in ee and decreasing adsorbed amount with increasing reduction temperature

In some applications, this compound(53562-86-0)COA of Formula: C5H10O3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about Ligand-acceleration by a chiral modifier in the enantioselective hydrogenation of methyl acetoacetate on a Raney nickel catalyst: effect of a modifier configuration.Recommanded Product: 53562-86-0.

Reaction rate and enantioselectivity of asym. hydrogenation of Me acetoacetate were studied over Raneynickel catalysts modified with (R,R)-tartaric acid, malic acid, or succinic acid to reveal the impacts of the modifier configuration. Catalysts comodified with two different acids were also examined to confirm the conclusions. From anal. of the enantiomer ratio of the hydrogenation product and initial reaction rate, tartaric acid (TA) was found to have dual functions as the modifier during the hydrogenation; effective suppression of the racemic catalysis on bare Ni surface and extensive enantiodifferentiating ligand acceleration by adsorbed TA. It was demonstrated that each adsorbed chiral modifier mol. independently takes part in the enantiospecific hydrogenation.

As far as I know, this compound(53562-86-0)Recommanded Product: 53562-86-0 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics