Studies on Development of Sufficiently Chemoselective N-Acylation Reagents: N-Acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides was written by Kondo, K.;Sekimoto, E.;Nakao, J.;Murakami, Y.. And the article was included in Tetrahedron in 2000.Safety of Benzyl 3-methylpiperazine-1-carboxylate This article mentions the following:
A variety of storable N-acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides, prepared from N-2,3,4,5,6-pentafluorophenylmethanesulfonamide, have been developed after systematic research on the structure-reactivity relationship and were found to serve as N-acylation reagents exhibiting sufficiently good chemoselectivity. In the experiment, the researchers used many compounds, for example, Benzyl 3-methylpiperazine-1-carboxylate (cas: 84477-85-0Safety of Benzyl 3-methylpiperazine-1-carboxylate).
Benzyl 3-methylpiperazine-1-carboxylate (cas: 84477-85-0) belongs to piperazine derivatives. Simple N-substituted piperazines have been found in many drug molecules. Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.Safety of Benzyl 3-methylpiperazine-1-carboxylate
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics